Dr. Ali Zarrabi is Associate Professor and Principal Investigator in the Biomedical Engineering Department of Istinye University. He holds a bachelor's degree of Chemical Engineering from Isfahan University of Technology, a master's degree of Chemical Engineering from Sharif University of Technology, and a PhD of Nanobiotechnology from Sharif University of Technology. His current research interests include nanobiotechnology, nanomedicine, drug delivery systems, nanotheranostics, nanomaterials, and surface engineering/modifications of nanomaterials. His group works at the interface of supramolecular chemistry, bioengineering, and medicine to develop approaches for simultaneous diagnosis and treatment of diseases. Dr. Zarrabi is a member of editorial board of several journals such as "Journal of Personalized medicine", "Bioengineering", "Future Pharmacology", "Biomaterials and Polymers Horizon", and "Nanofabrication".
Araştırma Alanları
- Nanomedicine
- Bioengineering
- Biomedical Engineering
- Biomaterials
- Theranostic Therapy
- Nano Based Therapeutics Geliştirilmesi
- Sağlıkta Nanoteknoloji
- Cancer
- Neurodegenrative Disease
- Alzheimer's Disease
- Parkinson's disease
- Glioblastoma; GBM
Çalışma Alanları
- Mühendislik Temel Alanı
- Biyomedikal Mühendisliği
- Biyomalzeme
- Biyoteknoloji
- Nanoteknoloji
- Application of Convergent Science and Technology toward Ocular Disease Treatment, 2023
- (Nano)platforms in breast cancer therapy: Drug/gene delivery, advanced nanocarriers and immunotherapy, 2023
- Graphene oxide nanoarchitectures in cancer biology: Nano-modulators of autophagy and apoptosis, 2023
- Advancements and Applications of Upconversion Nanoparticles in Wound Dressings, 2023
- Cancer stem cell-mediated drug resistance: A comprehensive gene expression profile analysis in breast cancer, 2023
- Biosensor integrated brain on a chip platforms: Progress and prospects in clinical translation, 2023
- Fabrication of a Dual-Drug-Loaded Smart Niosome-g-Chitosan Polymeric Platform for Lung Cancer Treatment, 2023
- Biomedical applications of engineered heparin-based materials, 2023
- Biosensor integrated brain-on-a-chip platforms: Progress and prospects in clinical translation, 2023
- Application of Convergent Science and Technology toward Ocular Disease Treatment, 2023
- Biosensor integrated brain-on-a-chip platforms: Progress and prospects in clinical translation, 2023
- Tackling chronic wound healing using nanomaterials: advancements, challenges, and future perspectives, 2023
- Application of Convergent Science and Technology toward Ocular Disease Treatment, 2023
- AMPK signaling in diabetes mellitus, insulin resistance and diabetic complications: A pre-clinical and clinical investigation, 2022
- Combination therapy using nanomaterials and stem cells to treat spinal cord injuries, 2022
- EZH2 as a new therapeutic target in brain tumors: Molecular landscape, therapeutic targeting and future prospects, 2022
- (Nano)platforms in bladder cancer therapy: Challenges and opportunities, 2022
- Targeting AMPK signaling in ischemic/reperfusion injury: From molecular mechanism to pharmacological interventions, 2022
- Gene regulation by antisense transcription: A focus on neurological and cancer diseases, 2022
- Noncoding RNAs and their therapeutics in paclitaxel chemotherapy: Mechanisms of initiation, progression, and drug sensitivity, 2022
- Development of Lateral Flow Assays for Rapid Detection of Troponin I: A Review, 2022
- Cellular targets and molecular activity mechanisms of bee venom in cancer: recent trends and developments, 2022
- Combination therapy using nanomaterials and stem cells to treat spinal cord injuries, 2022
- Association analysis of rs1800470 (T869C) variation in TGFB1 gene with the risk of ischemic stroke in Asian population, 2022
- Cellular targets and molecular activity mechanisms of bee venom in cancer: recent trends and developments, 2022
- Cellular targets and molecular activity mechanisms of bee venom in cancer: recent trends and developments, 2022
- Emerging role of exosomes in cancer progression and tumor microenvironment remodeling, 2022
- Graphene oxide quantum dot-chitosan nanotheranostic platform as a pH-responsive carrier for improving curcumin uptake internalization: In vitro & in silico study, 2022
- Nanotechnological Approaches in Prostate Cancer Therapy: Integration of engineering and biology, 2022
- Long noncoding RNAs (lncRNAs) in pancreatic cancer progression, 2022
- Chitosan-based nanoscale systems for doxorubicin delivery: Exploring biomedical application in cancer therapy, 2022
- Immunology Meets Bioengineering: Improving the Effectiveness of Glioblastoma Immunotherapy, 2022
- Long non-coding RNAs and exosomal lncRNAs: Potential functions in lung cancer progression, drug resistance and tumor microenvironment remodeling, 2022
- The convergence of in silico approach and nanomedicine for efficient cancer treatment; in vitro investigations on curcumin loaded multifunctional graphene oxide nanocomposite structure, 2022
- Exosomes as Promising Nanostructures in Diabetes Mellitus: From Insulin Sensitivity to Ameliorating Diabetic Complications, 2022
- The Importance of SNPs at miRNA Binding Sites as Biomarkers of Gastric and Colorectal Cancers: A Systematic Review, 2022
- AMPK signaling in diabetes mellitus, insulin resistance and diabetic complications: A pre-clinical and clinical investigation, 2022
- Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response, 2022
- Long non-coding RNAs as new players in bladder cancer: Lessons from pre-clinical and clinical studies, 2022
- Advances in understanding the role of P-gp in doxorubicin resistance: Molecular pathways, therapeutic strategies, and prospects, 2022
- Chitosan: A versatile bio-platform for breast cancer theranostics, 2022
- Mesoporous silica@chitosan@gold nanoparticles as \u201con/off\u201d optical biosensor and pH-sensitive theranostic platform against cancer, 2022
- Doxorubicin-loaded graphene oxide nanocomposites in cancer medicine: Stimuli-responsive carriers, co-delivery and suppressing resistance, 2022
- Targeted regulation of autophagy using nanoparticles: New insight into cancer therapy, 2022
- Targeting autophagy, oxidative stress, and ER stress for neurodegenerative diseases treatment, 2022
- Overcoming doxorubicin resistance in cancer: siRNA-loaded nanoarchitectures for cancer gene therapy, 2022
- Characterization and optical properties of mechanochemically synthesized molybdenum-doped rutile nanoparticles and their electronic structure studies by density functional theory, 2022
- The long and short non-coding RNAs modulating EZH2 signaling in cancer, 2022
- Exploiting Urazole’s Acidity for Fabrication of Hydrogels and Ion-Exchange Materials, 2021
- Citrus Genus and Its Waste Utilization: A Review on Health-Promoting Activities and Industrial Application, 2021
- Drug Delivery (Nano)Platforms for Oral and Dental Applications: Tissue Regeneration, Infection Control, and Cancer Management, 2021
- Lycopene: Food Sources, Biological Activities, and Human Health Benefits, 2021
- Mesoporous Bioactive Glasses in Cancer Diagnosis and Therapy: Stimuli\u2010Responsive, Toxicity, Immunogenicity, and Clinical Translation, 2021
- Revealing the role of miRNA-489 as a new onco-suppressor factor in different cancers based on pre-clinical and clinical evidence, 2021
- Functionalization of polymers and nanomaterials for water treatment, food packaging, textile and biomedical applications: a review, 2021
- Curcumin and inflammatory bowel diseases: From in vitro studies to clinical trials, 2021
- Lung cancer cells and their sensitivity/resistance to cisplatin chemotherapy: Role of microRNAs and upstream mediators, 2021
- Nrf2 signaling pathway in cisplatin chemotherapy: Potential involvement in organ protection and chemoresistance, 2021
- Flavonoids against the SARS-CoV-2 induced inflammatory storm, 2021
- Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects, 2021
- Electrospun nanocarriers for delivering natural products for cancer therapy, 2021
- Citrus Genus and Its Waste Utilization: A Review on Health-Promoting Activities and Industrial Application, 2021
- Cervical cancer progression is regulated by SOX transcription factors: Revealing signaling networks and therapeutic strategies, 2021
- Pre-clinical investigation of STAT3 pathway in bladder cancer: Paving the way for clinical translation, 2021
- Artemisia species as a new candidate for Diabetes therapy: A Comprehensive Review, 2021
- Quercetin and Its Nano-Scale Delivery Systems in Prostate Cancer Therapy: Paving the Way for Cancer Elimination and Reversing Chemoresistance, 2021
- Elucidating Role of Reactive Oxygen Species (ROS) in Cisplatin Chemotherapy: A Focus on Molecular Pathways and Possible Therapeutic Strategies, 2021
- MicroRNAs regulating SOX2 in cancer progression and therapy response, 2021
- The role of microRNA-338-3p in cancer: growth, invasion, chemoresistance, and mediators, 2021
- Dual relationship between long non-coding RNAs and STAT3 signaling in different cancers: New insight to proliferation and metastasis, 2021
- Novel strategy in breast cancer therapy: Revealing the bright side of ginsenosides, 2021
- Curcumin and inflammatory bowel diseases: From in vitro studies to clinical trials, 2021
- Small in Size, but Large in Action: microRNAs as Potential Modulators of PTEN in Breast and Lung Cancers, 2021
- Naringenin Nano-Delivery Systems and Their Therapeutic Applications, 2021
- Crosstalk of long non-coding RNAs and EMT: Searching the missing pieces of an incomplete puzzle for lung cancer therapy, 2021
- Current Trends in the Therapeutic Strategies for Diabetes Management, 2021
- Nrf2 Signaling Pathway in Chemoprotection and Doxorubicin Resistance: Potential Application in Drug Discovery, 2021
- The role of SOX family transcription factors in gastric cancer, 2021
- Synthesis of Curcumin Loaded Smart pH-Responsive Stealth Liposome as a Novel Nanocarrier for Cancer Treatment, 2021
- Injectable hyaluronic acid-based antibacterial hydrogel adorned with biogenically synthesized AgNPs-decorated multi-walled carbon nanotubes, 2021
- Small interfering RNA (siRNA) to target genes and molecular pathways in glioblastoma therapy: Current status with an emphasis on delivery systems, 2021
- Long non-coding RNAs in the doxorubicin resistance of cancer cells, 2021
- Employing siRNA tool and its delivery platforms in suppressing cisplatin resistance: Approaching to a new era of cancer chemotherapy, 2021
- Drug Delivery (Nano)Platforms for Oral and Dental Applications: Tissue Regeneration, Infection Control, and Cancer Management, 2021
- Nonspherical Metal\u2010Based Nanoarchitectures: Synthesis and Impact of Size, Shape, and Composition on Their Biological Activity, 2021
- Gallic acid for cancer therapy: Molecular mechanisms and boosting efficacy by nanoscopical delivery, 2021
- Long noncoding RNAs: A novel insight in the leukemogenesis and drug resistance in acute myeloid leukemia, 2021
- Advances in understanding the role of P-gp in doxorubicin resistance: Molecular pathways, therapeutic strategies, and prospects, 2021
- Revealing the role of miRNA-489 as a new onco-suppressor factor in different cancers based on pre-clinical and clinical evidence, 2021
- Long non-coding RNAs as new players in bladder cancer: Lessons from pre-clinical and clinical studies, 2021
- Benzimidazole analogues as efficient arsenals in war against methicillin-resistance staphylococcus aureus (MRSA) and its SAR studies, 2021
- Role of ZEB family members in proliferation, metastasis and chemoresistance of prostate cancer cells: Revealing signaling networks, 2021
- Advances in understanding the role of P-gp in doxorubicin resistance: Molecular pathways, therapeutic strategies, and prospects, 2021
- Regulation of Nuclear Factor-KappaB (NF-κB) signaling pathway by non-coding RNAs in cancer: Inhibiting or promoting carcinogenesis?, 2021
- Endocytosis of abiotic nanomaterials and nanobiovectors: Inhibition of membrane trafficking, 2021
- A review study on the modulation of SIRT1 expression by miRNAs in aging and age-associated diseases, 2021
- Long non-coding RNAs in the doxorubicin resistance of cancer cells, 2021
- AIE-featured tetraphenylethylene nanoarchitectures in biomedical application: Bioimaging, drug delivery and disease treatment, 2021
- Design and characterization of a novel pH-sensitive biocompatible and multifunctional nanocarrier for in vitro paclitaxel release, 2021
- Therapeutic potential of AMPK signaling targeting in lung cancer: Advances, challenges and future prospects, 2021
- New insight towards development of paclitaxel and docetaxel resistance in cancer cells: EMT as a novel molecular mechanism and therapeutic possibilities, 2021
- Antimicrobial peptides as potential therapeutics for breast cancer, 2021
- Drug Delivery (Nano)Platforms for Oral and Dental Applications: Tissue Regeneration, Infection Control, and Cancer Management, 2021
- Flavonoids against the SARS-CoV-2 induced inflammatory storm, 2021
- Electroconductive multi-functional polypyrrole composites for biomedical applications, 2021
- Interplay between SOX9 transcription factor and microRNAs in cancer, 2021
- Nonspherical Metal\u2010Based Nanoarchitectures: Synthesis and Impact of Size, Shape, and Composition on Their Biological Activity, 2021
- Effect of zinc-doped hydroxyapatite/graphene nanocomposite on the physicochemical properties and osteogenesis differentiation of 3D-printed polycaprolactone scaffolds for bone tissue engineering, 2021
- Development and optimization of a new hybrid chitosan-grafted graphene oxide/magnetic nanoparticle system for theranostic applications, 2021
- Self-assembled peptide and protein nanostructures for anti-cancer therapy: Targeted delivery, stimuli-responsive devices and immunotherapy, 2021
- Hyaluronic acid-based nanoplatforms for Doxorubicin: A review of stimuli-responsive carriers, co-delivery and resistance suppression, 2021
- Biomedical application of chitosan-based nanoscale delivery systems: Potential usefulness in siRNA delivery for cancer therapy, 2021
- Nrf2 signaling pathway in cisplatin chemotherapy: Potential involvement in organ protection and chemoresistance, 2021
- Caffeic acid and its derivatives as potential modulators of oncogenic molecular pathways: New hope in the fight against cancer, 2021
- The involvement of epithelial-to-mesenchymal transition in doxorubicin resistance: Possible molecular targets, 2021
- A reduced graphene oxide-β-cyclodextrin nanocomposite-based electrode for electrochemical detection of curcumin, 2021
- Non-spherical nanostructures in nanomedicine: From noble metal nanorods to transition metal dichalcogenide nanosheets, 2021
- In vivo gene delivery mediated by non-viral vectors for cancer therapy, 2020
- An adhesive and injectable nanocomposite hydrogel of thiolated gelatin/gelatin methacrylate/Laponite (R) as a potential surgical sealant, 2020
- Recent advances and future directions in anti\u2010tumor activity of cryptotanshinone: A mechanistic review, 2020
- The ER Stress/UPR Axis in Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis, 2020
- New Horizons in Hydrogels for Methotrexate Delivery, 2020
- Recent advances and future directions in anti\u2010tumor activity of cryptotanshinone: A mechanistic review, 2020
- Hierarchical multifunctional graphene oxide cancer nanotheranostics agent for synchronous switchable fluorescence imaging and chemical therapy, 2020
- Niosomal Drug Delivery Systems for Ocular Disease—Recent Advances and Future Prospects, 2020
- Functionalization of polymers and nanomaterials for water treatment, food packaging, textile and biomedical applications: a review, 2020
- Graphene oxide - silica composite aerogels as pharmaceutical nanocarriers, 2022
- SPIONs as Nano-Theranostics Agents, ISBN: 978-981-10-3563-0, 2017